Domain swap in the C-terminal ubiquitin-like domain of human doublecortin.

Rufer, Arne C; Kusznir, Eric; Burger, Dominique; Stihle, Martine; Ruf, Armin; Rudolph, Markus G

Rufer, Arne C; Kusznir, Eric; Burger, Dominique; Stihle, Martine; Ruf, Armin; Rudolph, Markus G.

Affiliation

Rufer AC; pRED, Therapeutic Modalities, F. Hoffmann-La Roche, 4070 Basel, Switzerland.
Kusznir E; pRED, Therapeutic Modalities, F. Hoffmann-La Roche, 4070 Basel, Switzerland.
Burger D; pRED, Therapeutic Modalities, F. Hoffmann-La Roche, 4070 Basel, Switzerland.
Stihle M; pRED, Therapeutic Modalities, F. Hoffmann-La Roche, 4070 Basel, Switzerland.
Ruf A; pRED, Therapeutic Modalities, F. Hoffmann-La Roche, 4070 Basel, Switzerland.
Rudolph MG; pRED, Therapeutic Modalities, F. Hoffmann-La Roche, 4070 Basel, Switzerland.

Acta Crystallogr D Struct Biol ; 74(Pt 5): 450-462, 2018 May 01.

Article in En | MEDLINE | ID: mdl-29717716

Subject(s)

Microtubule-Associated Proteins/chemistry; Neuropeptides/chemistry; Protein Domains; Crystallography, X-Ray; Doublecortin Domain Proteins; Humans; Lissencephaly/genetics; Microtubule-Associated Proteins/genetics; Microtubule-Associated Proteins/metabolism; Microtubules/metabolism; Mutation; Neuropeptides/genetics; Neuropeptides/metabolism; Protein Conformation; Protein Multimerization; Ubiquitin/chemistry; Ultracentrifugation

Key words

analytical ultracentrifugation; domain swap; double-cortex syndrome; doublecortin; lissencephaly; microtubule-associated protein

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Full text: 1 Database: MEDLINE Main subject: Neuropeptides / Protein Domains / Microtubule-Associated Proteins Limits: Humans Language: En Year: 2018 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Neuropeptides / Protein Domains / Microtubule-Associated Proteins Limits: Humans Language: En Year: 2018 Type: Article