microRNA-451a regulates colorectal cancer proliferation in response to radiation.

Ruhl, Rebecca; Rana, Shushan; Kelley, Katherine; Espinosa-Diez, Cristina; Hudson, Clayton; Lanciault, Christian; Thomas, Charles R; Liana Tsikitis, V; Anand, Sudarshan

Ruhl, Rebecca; Rana, Shushan; Kelley, Katherine; Espinosa-Diez, Cristina; Hudson, Clayton; Lanciault, Christian; Thomas, Charles R; Liana Tsikitis, V; Anand, Sudarshan.

Affiliation

Ruhl R; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Rana S; Department of Radiation Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Kelley K; Department of Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Espinosa-Diez C; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Hudson C; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Lanciault C; Department of Pathology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Thomas CR; Department of Radiation Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA.
Liana Tsikitis V; Department of Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. Tsikitis@ohsu.edu.
Anand S; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. anands@ohsu.edu.

BMC Cancer ; 18(1): 517, 2018 May 03.

Article in En | MEDLINE | ID: mdl-29720118

Subject(s)

Cell Proliferation/radiation effects; Colorectal Neoplasms/therapy; Gene Expression Regulation, Neoplastic/radiation effects; MicroRNAs/metabolism; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/metabolism; Animals; Calcium-Binding Proteins/genetics; Calcium-Binding Proteins/metabolism; Cell Proliferation/genetics; Chemoradiotherapy/methods; Colorectal Neoplasms/genetics; Colorectal Neoplasms/mortality; Datasets as Topic; Female; Gene Expression Profiling; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Repressor Proteins/genetics; Repressor Proteins/metabolism; Signal Transduction/genetics; Survival Analysis; Up-Regulation; Xenograft Model Antitumor Assays

Key words

CAB39; Colorectal cancer; EMSY; Radiation therapy; microRNAs

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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Gene Expression Regulation, Neoplastic / MicroRNAs / Cell Proliferation Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2018 Type: Article

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