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A phase I trial to determine safety and pharmacokinetics of ASLAN002, an oral MET superfamily kinase inhibitor, in patients with advanced or metastatic solid cancers.
Roohullah, Aflah; Cooper, Adam; Lomax, Anna J; Aung, Jennifer; Barge, Alan; Chow, Lilian; McHale, Mark; Desai, Jayesh; Whittle, James R; Tran, Ben; de Souza, Paul; Horvath, Lisa G.
Affiliation
  • Roohullah A; Liverpool Cancer Therapy Centre, Corner of Goulburn & Elizabeth Streets, Liverpool, NSW, 2170, Australia.
  • Cooper A; Western Sydney University, Campbelltown, NSW, Australia.
  • Lomax AJ; Liverpool Cancer Therapy Centre, Corner of Goulburn & Elizabeth Streets, Liverpool, NSW, 2170, Australia.
  • Aung J; Western Sydney University, Campbelltown, NSW, Australia.
  • Barge A; Chris O'Brien Lifehouse, Department of Medical Oncology, Camperdown, NSW, Australia.
  • Chow L; Liverpool Cancer Therapy Centre, Corner of Goulburn & Elizabeth Streets, Liverpool, NSW, 2170, Australia.
  • McHale M; Aslan Pharmaceuticals Pte Ltd, 83 Clemenceau Avenue, Singapore, 239920, Singapore.
  • Desai J; Aslan Pharmaceuticals Pte Ltd, 83 Clemenceau Avenue, Singapore, 239920, Singapore.
  • Whittle JR; Aslan Pharmaceuticals Pte Ltd, 83 Clemenceau Avenue, Singapore, 239920, Singapore.
  • Tran B; Department of Medical Oncology, Royal Melbourne Hospital, Grattan Street, Prahran, VIC, 3050, Australia.
  • de Souza P; Department of Medical Oncology, Royal Melbourne Hospital, Grattan Street, Prahran, VIC, 3050, Australia.
  • Horvath LG; Department of Medical Oncology, Royal Melbourne Hospital, Grattan Street, Prahran, VIC, 3050, Australia.
Invest New Drugs ; 36(5): 886-894, 2018 10.
Article in En | MEDLINE | ID: mdl-29766337
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Full text: 1 Database: MEDLINE Main subject: Proto-Oncogene Proteins c-met / Protein Kinase Inhibitors / Neoplasms Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Proto-Oncogene Proteins c-met / Protein Kinase Inhibitors / Neoplasms Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Year: 2018 Type: Article