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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.
Skucha, Anna; Ebner, Jessica; Schmöllerl, Johannes; Roth, Mareike; Eder, Thomas; César-Razquin, Adrián; Stukalov, Alexey; Vittori, Sarah; Muhar, Matthias; Lu, Bin; Aichinger, Martin; Jude, Julian; Müller, André C; Gyorffy, Balázs; Vakoc, Christopher R; Valent, Peter; Bennett, Keiryn L; Zuber, Johannes; Superti-Furga, Giulio; Grebien, Florian.
Affiliation
  • Skucha A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
  • Ebner J; Ludwig Boltzmann Institute for Cancer Research, Vienna, 1090, Austria.
  • Schmöllerl J; Ludwig Boltzmann Institute for Cancer Research, Vienna, 1090, Austria.
  • Roth M; Ludwig Boltzmann Institute for Cancer Research, Vienna, 1090, Austria.
  • Eder T; Research Institute of Molecular Pathology, Vienna, 1030, Austria.
  • César-Razquin A; Ludwig Boltzmann Institute for Cancer Research, Vienna, 1090, Austria.
  • Stukalov A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
  • Vittori S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
  • Muhar M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
  • Lu B; Research Institute of Molecular Pathology, Vienna, 1030, Austria.
  • Aichinger M; Cold Spring Harbor Larboratory, Cold Spring Harbor, 11724, NY, USA.
  • Jude J; Research Institute of Molecular Pathology, Vienna, 1030, Austria.
  • Müller AC; Research Institute of Molecular Pathology, Vienna, 1030, Austria.
  • Gyorffy B; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
  • Vakoc CR; MTA TTK Lendület Cancer Biomarker Research Group, Institute of Enzymology, Second Department of Pediatrics, Semmelweis University, Budapest, 1094, Hungary.
  • Valent P; Cold Spring Harbor Larboratory, Cold Spring Harbor, 11724, NY, USA.
  • Bennett KL; Department of Internal Medicine I. Division of Hematology and Hemostaseology, Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, 1090, Austria.
  • Zuber J; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
  • Superti-Furga G; Research Institute of Molecular Pathology, Vienna, 1030, Austria.
  • Grebien F; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, 1090, Austria.
Nat Commun ; 9(1): 1983, 2018 05 18.
Article in En | MEDLINE | ID: mdl-29777171
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Full text: 1 Database: MEDLINE Main subject: Leukemia / Oncogene Proteins, Fusion / Histone-Lysine N-Methyltransferase / Myeloid-Lymphoid Leukemia Protein Limits: Humans Language: En Year: 2018 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Leukemia / Oncogene Proteins, Fusion / Histone-Lysine N-Methyltransferase / Myeloid-Lymphoid Leukemia Protein Limits: Humans Language: En Year: 2018 Type: Article