Effect of lipoprotein-associated phospholipase A2 inhibitor on insulin resistance in streptozotocin-induced diabetic pregnant rats.

Wang, Guo-Hua; Jin, Jun; Sun, Li-Zhou

Wang, Guo-Hua; Jin, Jun; Sun, Li-Zhou.

Affiliation

Wang GH; Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China.
Jin J; Department of Obstetrics and Gynecology, The First People's Hospital of Lianyungang City, Affiliated Hospital of Xuzhou Medical University, Lianyungang 222000, China.
Sun LZ; Department of Clinical Laboratory, The First People's Hospital of Lianyungang City, Affiliated Hospital of Xuzhou Medical University, Lianyungang 222000, China.

Endocr J ; 65(9): 903-913, 2018 Sep 27.

Article in En | MEDLINE | ID: mdl-29925744

Subject(s)

1-Alkyl-2-acetylglycerophosphocholine Esterase/antagonists & inhibitors; Benzaldehydes/pharmacology; Diabetes Mellitus, Experimental/metabolism; Enzyme Inhibitors/pharmacology; Insulin Resistance; Oximes/pharmacology; Pregnancy in Diabetics/metabolism; Animals; Benzaldehydes/therapeutic use; Blood Glucose/metabolism; Diabetes Mellitus, Experimental/chemically induced; Diabetes Mellitus, Experimental/drug therapy; Diabetes Mellitus, Experimental/pathology; Female; Insulin/blood; Islets of Langerhans/drug effects; Islets of Langerhans/metabolism; Male; Oximes/therapeutic use; Pregnancy; Pregnancy in Diabetics/drug therapy; Pregnancy in Diabetics/pathology; Rats; Rats, Sprague-Dawley; Streptozocin

Key words

Darapladib; Insulin resistance; Lipoprotein-associated phospholipase A2

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Full text: 1 Database: MEDLINE Main subject: Oximes / Pregnancy in Diabetics / Benzaldehydes / Insulin Resistance / 1-Alkyl-2-acetylglycerophosphocholine Esterase / Diabetes Mellitus, Experimental / Enzyme Inhibitors Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Pregnancy Language: En Year: 2018 Type: Article

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