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A Semi-Physiologically Based Pharmacokinetic Model Describing the Altered Metabolism of Midazolam Due to Inflammation in Mice.
Varkhede, Ninad; Patel, Nita; Chang, William; Ruterbories, Kenneth; Forrest, M Laird.
Affiliation
  • Varkhede N; Department of Pharmaceutical Chemistry, The University of Kansas, 2095 Constant Ave, Lawrence, Kansas, 66047, USA.
  • Patel N; Drug Disposition, Lilly Corporate Center, Eli Lilly and Company, Indianapolis, Indiana, 46285, USA.
  • Chang W; Lilly Biotechnology, Eli Lilly and Company, San Diego, California, 92121, USA.
  • Ruterbories K; Bioanalysis and Biotransformation, Research and Development, AbbVie, North Chicago, Illinois, USA.
  • Forrest ML; Department of Pharmaceutical Chemistry, The University of Kansas, 2095 Constant Ave, Lawrence, Kansas, 66047, USA. lforrest@ku.edu.
Pharm Res ; 35(8): 162, 2018 06 21.
Article in En | MEDLINE | ID: mdl-29931580
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Full text: 1 Database: MEDLINE Main subject: Midazolam / Inflammation / Adjuvants, Anesthesia Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Midazolam / Inflammation / Adjuvants, Anesthesia Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2018 Type: Article