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Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo.
Laconi, Andrea; van Beurden, Steven J; Berends, Alinda J; Krämer-Kühl, Annika; Jansen, Christine A; Spekreijse, Dieuwertje; Chénard, Gilles; Philipp, Hans-Christian; Mundt, Egbert; Rottier, Peter J M; Hélène Verheije, M.
Affiliation
  • Laconi A; 1​Faculty of Veterinary Medicine, Department Pathobiology, Pathology Division, Utrecht University, Utrecht, 3584CL, The Netherlands.
  • van Beurden SJ; †â€‹Present address: Gupta Strategists, Ophemert, The Netherlands.
  • Berends AJ; 1​Faculty of Veterinary Medicine, Department Pathobiology, Pathology Division, Utrecht University, Utrecht, 3584CL, The Netherlands.
  • Krämer-Kühl A; 1​Faculty of Veterinary Medicine, Department Pathobiology, Pathology Division, Utrecht University, Utrecht, 3584CL, The Netherlands.
  • Jansen CA; 2​Boehringer Ingelheim Veterinary Research Center GmbH & Co. KG, Hannover, Germany.
  • Spekreijse D; 3​Faculty of Veterinary Medicine, Department Infectious Diseases and Immunology, Immunology Division, Utrecht University, Utrecht, 3584CL, The Netherlands.
  • Chénard G; ‡â€‹Present address: Intravacc Animal Research Centre, Ponwalla Science Park, The Netherlands.
  • Philipp HC; 4​Boehringer Ingelheim Animal Health Operations BV, Weesp, The Netherlands.
  • Mundt E; §â€‹Present address: Thermo Fisher Scientific, 8211AR Lelystad, The Netherlands.
  • Rottier PJM; 4​Boehringer Ingelheim Animal Health Operations BV, Weesp, The Netherlands.
  • Hélène Verheije M; 2​Boehringer Ingelheim Veterinary Research Center GmbH & Co. KG, Hannover, Germany.
J Gen Virol ; 2018 Aug 01.
Article in En | MEDLINE | ID: mdl-30067172
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Full text: 1 Database: MEDLINE Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Language: En Year: 2018 Type: Article