Uptake of Neisserial autotransporter lipoprotein (NalP) promotes an increase in human brain microvascular endothelial cell metabolic activity.

Dufailu, Osman A; Mahdavi, Jafar; Ala'Aldeen, Dlawer A A; Wooldridge, Karl G; Oldfield, Neil J

Dufailu, Osman A; Mahdavi, Jafar; Ala'Aldeen, Dlawer A A; Wooldridge, Karl G; Oldfield, Neil J.

Affiliation

Dufailu OA; School of Life Sciences, University of Nottingham, Nottingham, UK.
Mahdavi J; School of Life Sciences, University of Nottingham, Nottingham, UK.
Ala'Aldeen DAA; School of Life Sciences, University of Nottingham, Nottingham, UK.
Wooldridge KG; School of Life Sciences, University of Nottingham, Nottingham, UK.
Oldfield NJ; School of Life Sciences, University of Nottingham, Nottingham, UK. Electronic address: neil.oldfield@nottingham.ac.uk.

Microb Pathog ; 124: 70-75, 2018 Nov.

Article in En | MEDLINE | ID: mdl-30081080

Subject(s)

Endothelial Cells/drug effects; Endothelial Cells/metabolism; Membrane Transport Proteins/metabolism; Serine Endopeptidases/metabolism; Cells, Cultured; DNA Mutational Analysis; Flow Cytometry; Humans; Membrane Transport Proteins/genetics; Microscopy, Confocal; Mutagenesis, Site-Directed; Protein Transport; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Serine Endopeptidases/genetics

Key words

Autotransporter; Cellular uptake; NalP; Neisseria meningitidis; Pathogenesis; Proteolysis

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Full text: 1 Database: MEDLINE Main subject: Membrane Transport Proteins / Serine Endopeptidases / Endothelial Cells Limits: Humans Language: En Year: 2018 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Membrane Transport Proteins / Serine Endopeptidases / Endothelial Cells Limits: Humans Language: En Year: 2018 Type: Article