Synthesis of 2,2-Dialkyl Chromanes by Intramolecular Ullmann C-O Coupling Reactions toward the Total Synthesis of D-&#945;-Tocopherol.

Tsubogo, Tetsu; Aoyama, Saki; Takeda, Rika; Uchiro, Hiromi

Synthesis of 2,2-Dialkyl Chromanes by Intramolecular Ullmann C-O Coupling Reactions toward the Total Synthesis of D-α-Tocopherol.

Tsubogo, Tetsu; Aoyama, Saki; Takeda, Rika; Uchiro, Hiromi.

Affiliation

Tsubogo T; Faculty of Pharmaceutical Sciences, Tokyo University of Science.
Aoyama S; Division of Fusion of Regenerative Medicine with DDS, Research Institute for Science and Technology (RIST), Tokyo University of Science.
Takeda R; Faculty of Pharmaceutical Sciences, Tokyo University of Science.
Uchiro H; Faculty of Pharmaceutical Sciences, Tokyo University of Science.

Chem Pharm Bull (Tokyo) ; 66(9): 843-846, 2018.

Article in En | MEDLINE | ID: mdl-30175739

Subject(s)

Chromans/chemical synthesis; alpha-Tocopherol/chemical synthesis; Alcohols/chemistry; Amides/chemistry; Catalysis; Cyclization; Isomerism; Molecular Structure; Oxidation-Reduction

Key words

2,2-dialkyl chromane; D-α-tocopherol; Ullmann CO coupling reaction

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