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Structural alterations based on naproxen scaffold: Synthesis, evaluation of antitumor activity and COX-2 inhibition, and molecular docking.
El-Husseiny, Walaa M; El-Sayed, Magda A-A; Abdel-Aziz, Naglaa I; El-Azab, Adel S; Asiri, Yousif A; Abdel-Aziz, Alaa A-M.
Affiliation
  • El-Husseiny WM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
  • El-Sayed MA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University, New Damietta, Egypt.
  • Abdel-Aziz NI; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa City, Egypt.
  • El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia; Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo, 11884, Egypt.
  • Asiri YA; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
  • Abdel-Aziz AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia. Electronic address: almoenes@ksu.edu.sa.
Eur J Med Chem ; 158: 134-143, 2018 Oct 05.
Article in En | MEDLINE | ID: mdl-30216848
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Full text: 1 Database: MEDLINE Main subject: Naproxen / Cyclooxygenase 2 Inhibitors / Antineoplastic Agents Limits: Humans Language: En Year: 2018 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Naproxen / Cyclooxygenase 2 Inhibitors / Antineoplastic Agents Limits: Humans Language: En Year: 2018 Type: Article