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Towards establishing a minimal nanoparticle concentration for applications involving surface enhanced spatially offset resonance Raman spectroscopy (SESORRS) in vivo.
Nicolson, Fay; Jamieson, Lauren E; Mabbott, Samuel; Plakas, Konstantinos; Shand, Neil C; Detty, Michael R; Graham, Duncan; Faulds, Karen.
Affiliation
  • Nicolson F; Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow G1 1RD, UK. karen.faulds@strath.ac.uk.
Analyst ; 143(22): 5358-5363, 2018 Nov 05.
Article in En | MEDLINE | ID: mdl-30325368
ABSTRACT
Resonant chalcogenpyrylium nanotags demonstrate an exceptional surface enhanced Raman scattering (SERS) performance for use in SORS applications. Using surface enhanced spatially offset Raman spectroscopy (SESORS), nanotags modified with a chalcogenpyrylium dye were observed at concentrations as low as 1 pM through 5 mm of tissue. Calculated limits of detection suggest that these SERS nanotags can be detected at 104 fM using surface enhanced spatially offset resonance Raman scattering (SESORRS) demonstrating their potential for in vivo applications.
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Full text: 1 Database: MEDLINE Main subject: Organoselenium Compounds / Nanoparticles / Heterocyclic Compounds, 1-Ring Limits: Animals Language: En Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Organoselenium Compounds / Nanoparticles / Heterocyclic Compounds, 1-Ring Limits: Animals Language: En Year: 2018 Type: Article