Stimulating effect of heat shock on the early stage of human cytomegalovirus replication cycle.
Virus Res
; 6(3): 211-6, 1986 Dec.
Article
in En
| MEDLINE
| ID: mdl-3033930
ABSTRACT
The effect of mild heat shock on the replication of human cytomegalovirus (HCMV) was studied in human embryo fibroblasts. Treatment of cell cultures at 44 degrees C for 10 min just before infection or at 24 h post infection (p.i.) shortened HCMV eclipse period and enhanced viral replication, while heat shock performed at 48 h p.i. had no effect on the HCMV replication cycle. Study of HCMV-induced early and late antigens confirmed that the cellular response to heat shock influences HCMV replication in the early stage of the viral replication cycle.
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Database:
MEDLINE
Main subject:
Virus Replication
/
Immediate-Early Proteins
/
Cytomegalovirus
Limits:
Humans
Language:
En
Year:
1986
Type:
Article