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LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients.
Xie, Yuan; Sundström, Anders; Maturi, Naga P; Tan, E-Jean; Marinescu, Voichita D; Jarvius, Malin; Tirfing, Malin; Jin, Chuan; Chen, Lei; Essand, Magnus; Swartling, Fredrik J; Nelander, Sven; Jiang, Yiwen; Uhrbom, Lene.
Affiliation
  • Xie Y; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Sundström A; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Maturi NP; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Tan EJ; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Marinescu VD; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Jarvius M; Department of Medical Biochemistry and Microbiology, Biomedical Centre, Uppsala University and Science for Life Laboratory, Uppsala, Sweden.
  • Tirfing M; Department of Medical Sciences, Cancer Pharmacology and Computational Medicine, Uppsala University and Science for Life Laboratory, Uppsala, Sweden.
  • Jin C; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Chen L; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Essand M; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Swartling FJ; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Nelander S; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Jiang Y; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
  • Uhrbom L; Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.
J Pathol ; 247(2): 228-240, 2019 02.
Article in En | MEDLINE | ID: mdl-30357839
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Brain Neoplasms / Cell Movement / Glioblastoma / Receptors, G-Protein-Coupled / Cell Proliferation Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Brain Neoplasms / Cell Movement / Glioblastoma / Receptors, G-Protein-Coupled / Cell Proliferation Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2019 Type: Article