Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation.

Liu, Hongnan; Tan, Bie; Huang, Bo; Li, Jianjun; Wang, Jing; Liao, Peng; Guan, Guiping; Ji, Peng; Yin, Yulong

Liu, Hongnan; Tan, Bie; Huang, Bo; Li, Jianjun; Wang, Jing; Liao, Peng; Guan, Guiping; Ji, Peng; Yin, Yulong.

Affiliation

Liu H; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Tan B; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Huang B; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Li J; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Wang J; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Liao P; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Guan G; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of
Ji P; 4Department of Nutrition,University of California,Davis,CA 95616,USA.
Yin Y; 1Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Institute of Subtropical Agriculture,Chinese Academy of

Br J Nutr ; 120(12): 1321-1331, 2018 12.

Article in En | MEDLINE | ID: mdl-30375295

Subject(s)

Amino Acids, Aromatic/administration & dosage; Inflammation/metabolism; Intestines/pathology; Receptors, Calcium-Sensing/metabolism; Animals; Colon/metabolism; Cytokines/blood; Diet; Dietary Supplements; Epithelial Cells/metabolism; Female; I-kappa B Kinase/metabolism; Jejunum/metabolism; Lipopolysaccharides; NF-kappa B/metabolism; Peroxidase/metabolism; Phenylalanine/administration & dosage; Phosphorylation; RNA, Messenger/metabolism; Random Allocation; Signal Transduction; Sus scrofa; Swine; Tryptophan/administration & dosage; Tumor Necrosis Factor-alpha/metabolism; Tyrosine/administration & dosage

Key words

BW body weight; CCL2 CC chemokine ligand 2; CaSR calcium-sensing receptor; GM-CSF granulocytemacrophage colony-stimulating factor; IKK inhibitor of NF-κB kinase; IκB inhibitor of NF-κB; LPS lipopolysaccharide; MCP monocyte chemoattractant protein; MPO myeloperoxidase; PLC phospholipase C; Phe phenylalanine; TGF transforming growth factor; TPT tryptophan phenylalanine and tyrosine; Trp tryptophan; Tyr tyrosine; p-NF-κB phosphorylated NF-κB; Aromatic amino acids; Calcium-sensing receptor; Inflammatory response; Piglet model

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Full text: 1 Database: MEDLINE Main subject: Amino Acids, Aromatic / Receptors, Calcium-Sensing / Inflammation / Intestines Type of study: Prognostic_studies Limits: Animals Language: En Year: 2018 Type: Article

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