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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
Richter, Hans; Satz, Alexander L; Bedoucha, Marc; Buettelmann, Bernd; Petersen, Ann C; Harmeier, Anja; Hermosilla, Ricardo; Hochstrasser, Remo; Burger, Dominique; Gsell, Bernard; Gasser, Rodolfo; Huber, Sylwia; Hug, Melanie N; Kocer, Buelent; Kuhn, Bernd; Ritter, Martin; Rudolph, Markus G; Weibel, Franziska; Molina-David, Judith; Kim, Jin-Ju; Santos, Javier Varona; Stihle, Martine; Georges, Guy J; Bonfil, R Daniel; Fridman, Rafael; Uhles, Sabine; Moll, Solange; Faul, Christian; Fornoni, Alessia; Prunotto, Marco.
Affiliation
  • Richter H; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Satz AL; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Bedoucha M; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Buettelmann B; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Petersen AC; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Harmeier A; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Hermosilla R; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Hochstrasser R; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Burger D; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Gsell B; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Gasser R; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Huber S; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Hug MN; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Kocer B; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Kuhn B; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Ritter M; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Rudolph MG; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Weibel F; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Molina-David J; Ridgeline Therapeutics GmbH , Basel 4070 , Switzerland.
  • Kim JJ; Katz Family Division of Nephrology and Hypertension , University of Miami Miller School of Medicine , Miami , Florida 33136 , United States.
  • Santos JV; Peggy and Harold Katz Family Drug Discovery Center , University of Miami Miller School of Medicine , Miami , Florida 33136 , United States.
  • Stihle M; Katz Family Division of Nephrology and Hypertension , University of Miami Miller School of Medicine , Miami , Florida 33136 , United States.
  • Georges GJ; Peggy and Harold Katz Family Drug Discovery Center , University of Miami Miller School of Medicine , Miami , Florida 33136 , United States.
  • Bonfil RD; Katz Family Division of Nephrology and Hypertension , University of Miami Miller School of Medicine , Miami , Florida 33136 , United States.
  • Fridman R; Peggy and Harold Katz Family Drug Discovery Center , University of Miami Miller School of Medicine , Miami , Florida 33136 , United States.
  • Uhles S; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
  • Moll S; Roche Pharma Research and Early Development, Roche Innovation Center , Munich 82377 , Germany.
  • Faul C; Department of Pathology, College of Medical Sciences , Nova Southeastern University , Fort Lauderdale , Florida 33328 , United States.
  • Fornoni A; Department of Pathology , Wayne State University , Detroit , Michigan 48202 , United States.
  • Prunotto M; Roche Pharma Research and Early Development, Roche Innovation Center , Basel 4070 , Switzerland.
ACS Chem Biol ; 14(1): 37-49, 2019 01 18.
Article in En | MEDLINE | ID: mdl-30452219

Full text: 1 Database: MEDLINE Main subject: DNA / Discoidin Domain Receptor 1 / Kidney / Nephritis, Hereditary Limits: Animals Language: En Year: 2019 Type: Article

Full text: 1 Database: MEDLINE Main subject: DNA / Discoidin Domain Receptor 1 / Kidney / Nephritis, Hereditary Limits: Animals Language: En Year: 2019 Type: Article