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R-loop formation during S phase is restricted by PrimPol-mediated repriming.
Svikovic, Sasa; Crisp, Alastair; Tan-Wong, Sue Mei; Guilliam, Thomas A; Doherty, Aidan J; Proudfoot, Nicholas J; Guilbaud, Guillaume; Sale, Julian E.
Affiliation
  • Svikovic S; MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Crisp A; MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Tan-Wong SM; Sir William Dunn School of Pathology, Oxford, UK.
  • Guilliam TA; Genome Damage & Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Doherty AJ; Genome Damage & Stability Centre, School of Life Sciences, University of Sussex, Brighton, UK.
  • Proudfoot NJ; Sir William Dunn School of Pathology, Oxford, UK.
  • Guilbaud G; MRC Laboratory of Molecular Biology, Cambridge, UK.
  • Sale JE; MRC Laboratory of Molecular Biology, Cambridge, UK jes@mrc-lmb.cam.ac.uk.
EMBO J ; 38(3)2019 02 01.
Article in En | MEDLINE | ID: mdl-30478192
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Full text: 1 Database: MEDLINE Main subject: DNA, Single-Stranded / S Phase / DNA Primase / DNA-Directed DNA Polymerase / DNA Replication / G-Quadruplexes / Multifunctional Enzymes / R-Loop Structures Limits: Animals / Humans Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: DNA, Single-Stranded / S Phase / DNA Primase / DNA-Directed DNA Polymerase / DNA Replication / G-Quadruplexes / Multifunctional Enzymes / R-Loop Structures Limits: Animals / Humans Language: En Year: 2019 Type: Article