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Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair.
Kallimasioti-Pazi, Eirini M; Thelakkad Chathoth, Keerthi; Taylor, Gillian C; Meynert, Alison; Ballinger, Tracy; Kelder, Martijn J E; Lalevée, Sébastien; Sanli, Ildem; Feil, Robert; Wood, Andrew J.
Affiliation
  • Kallimasioti-Pazi EM; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
  • Thelakkad Chathoth K; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
  • Taylor GC; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
  • Meynert A; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
  • Ballinger T; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
  • Kelder MJE; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
  • Lalevée S; Institute of Molecular Genetics of Montpellier (IGMM), CNRS and University of Montpellier, Montpellier, France.
  • Sanli I; Institute of Molecular Genetics of Montpellier (IGMM), CNRS and University of Montpellier, Montpellier, France.
  • Feil R; Institute of Molecular Genetics of Montpellier (IGMM), CNRS and University of Montpellier, Montpellier, France.
  • Wood AJ; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
PLoS Biol ; 16(12): e2005595, 2018 12.
Article in En | MEDLINE | ID: mdl-30540740

Full text: 1 Database: MEDLINE Main subject: Heterochromatin / DNA Repair Limits: Animals Language: En Year: 2018 Type: Article

Full text: 1 Database: MEDLINE Main subject: Heterochromatin / DNA Repair Limits: Animals Language: En Year: 2018 Type: Article