Lung transplantation in two cystic fibrosis patients infected with previously pandrug-resistant Burkholderia cepacia complex treated with ceftazidime-avibactam.
Infection
; 47(2): 289-292, 2019 Apr.
Article
in En
| MEDLINE
| ID: mdl-30565008
ABSTRACT
We describe two cystic fibrosis patients infected with pandrug-resistant Burkholderia cepacia complex, with the exception of ceftazidime-avibactam, who received prophylaxis with this antibiotic during lung transplantation. Although both patients had a post-operative relapse of respiratory infection, one with positive blood cultures, ceftazidime-avibactam treatment yielded a favourable outcome. 12 months after transplantation, one patient presented an excellent clinical outcome. However, the other patient died 10 months later due to severe B. cepacia sinusitis with intracranial invasion.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Ceftazidime
/
Lung Transplantation
/
Drug Resistance, Multiple, Bacterial
/
Burkholderia cepacia complex
/
Azabicyclo Compounds
/
Anti-Bacterial Agents
Type of study:
Etiology_studies
Limits:
Adult
/
Humans
/
Male
Language:
En
Year:
2019
Type:
Article