Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds.

Kaadt, Erik; Alsing, Sidsel; Cecchi, Claudia R; Damgaard, Christian Kroun; Corydon, Thomas J; Aagaard, Lars.

Affiliation

Kaadt E; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Alsing S; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Cecchi CR; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Damgaard CK; Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.
Corydon TJ; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark.
Aagaard L; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark. Electronic address: aagaard@biomed.au.dk.

Mol Ther Nucleic Acids ; 14: 318-328, 2019 Mar 01.

Article in En | MEDLINE | ID: mdl-30654192