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New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies.
Abd El-Karim, Somaia S; Syam, Yasmin M; El Kerdawy, Ahmed M; Abdelghany, Tamer M.
Affiliation
  • Abd El-Karim SS; Therapeutical Chemistry Department, National Research Centre, Dokki, Cairo, P. O. Box 12622, Egypt.
  • Syam YM; Therapeutical Chemistry Department, National Research Centre, Dokki, Cairo, P. O. Box 12622, Egypt. Electronic address: yasmin_syam@yahoo.com.
  • El Kerdawy AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, P.O. Box 11562, Egypt; Molecular Modeling Unit, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, P.O. Box 11562, Egypt; Department of Pharmaceutical Chemistry, Faculty of Phar
  • Abdelghany TM; Department of Pharmacology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, P.O. Box 11787, Egypt.
Bioorg Chem ; 86: 80-96, 2019 05.
Article in En | MEDLINE | ID: mdl-30685646
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Full text: 1 Database: MEDLINE Main subject: Quantitative Structure-Activity Relationship / Protein Kinase Inhibitors / Cyclin-Dependent Kinase 2 / Molecular Docking Simulation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Year: 2019 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Quantitative Structure-Activity Relationship / Protein Kinase Inhibitors / Cyclin-Dependent Kinase 2 / Molecular Docking Simulation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Year: 2019 Type: Article