Effect of salt intake reduction on nocturia in patients with excessive salt intake.
Neurourol Urodyn
; 38(3): 927-933, 2019 03.
Article
in En
| MEDLINE
| ID: mdl-30706965
ABSTRACT
AIMS:
To assess the efficacy of salt reduction for improving nocturia in patients with high salt intake.METHODS:
Changes in lower urinary symptoms and frequency volume chart by salt intake (men 8 g/day; women ≥7 g/day) were analyzed in this prospective study. Patients were instructed to use a brochure for salt intake restriction via interview once every four weeks. The daily salt intake was estimated by using spot urine samples.RESULTS:
Two-hundred twenty-three (69.5%) patients were successful in reducing their daily salt intake (S group), whereas 98 (30.5%) patients failed to reduce their salt intake (F group). In the S group, nocturia improved from 2.3 ± 0.9 to 1.4 ± 1.0, and nocturnal polyuria index (NPi) improved from 30.2 ± 7.5 to 27.7 ± 7.3% (P < 0.001). In the Core Lower Urinary Tract Symptom Score (CLSS) of the S group, Q3 (urgency) improved from 1.0 ± 1.0 to 0.9 ± 1.0 (P = 0.001); Q1 (diurnal frequency) (P < 0.001), and Q2 (nocturia) also improved (P < 0.001). Moreover, the quality of life parameter improved significantly (P < 0.001). The patients in the F group did not have improvements in any symptom during the study period.CONCLUSIONS:
Patients with nocturia who also have high salt intake should be advised to reduce their salt intake, as a lifestyle modification. Our results support the importance of randomized clinical trials with larger populations and the appropriate inclusion/exclusion criteria to conclude the clinical usefulness of salt reduction in this patient cohort.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Sodium Chloride, Dietary
/
Diet, Sodium-Restricted
/
Nocturia
Type of study:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Year:
2019
Type:
Article