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CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.
Oostindie, Simone C; van der Horst, Hilma J; Lindorfer, Margaret A; Cook, Erika M; Tupitza, Jillian C; Zent, Clive S; Burack, Richard; VanDerMeid, Karl R; Strumane, Kristin; Chamuleau, Martine E D; Mutis, Tuna; de Jong, Rob N; Schuurman, Janine; Breij, Esther C W; Beurskens, Frank J; Parren, Paul W H I; Taylor, Ronald P.
Affiliation
  • Oostindie SC; Genmab, Utrecht, the Netherlands sio@genmab.com.
  • van der Horst HJ; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Lindorfer MA; Department of Hematology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Cook EM; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
  • Tupitza JC; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
  • Zent CS; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
  • Burack R; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
  • VanDerMeid KR; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
  • Strumane K; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
  • Chamuleau MED; Genmab, Utrecht, the Netherlands.
  • Mutis T; Department of Hematology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • de Jong RN; Department of Hematology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Schuurman J; Genmab, Utrecht, the Netherlands.
  • Breij ECW; Genmab, Utrecht, the Netherlands.
  • Beurskens FJ; Genmab, Utrecht, the Netherlands.
  • Parren PWHI; Genmab, Utrecht, the Netherlands.
  • Taylor RP; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
Haematologica ; 104(9): 1841-1852, 2019 09.
Article in En | MEDLINE | ID: mdl-30792198
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Full text: 1 Database: MEDLINE Main subject: Complement System Proteins / Immunoglobulin Fc Fragments / Leukemia, Lymphocytic, Chronic, B-Cell / Antigens, CD20 / Antibodies, Monoclonal, Humanized / Tetraspanins / Antigens, Neoplasm Limits: Humans Language: En Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Complement System Proteins / Immunoglobulin Fc Fragments / Leukemia, Lymphocytic, Chronic, B-Cell / Antigens, CD20 / Antibodies, Monoclonal, Humanized / Tetraspanins / Antigens, Neoplasm Limits: Humans Language: En Year: 2019 Type: Article