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Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment.
Ochiai, Nagahiro; Nakachi, Yutaka; Yokoo, Tomotaka; Ichihara, Takahiro; Eriksson, Tore; Yonemoto, Yuki; Kato, Takehiko; Ogata, Hitoshi; Fujimoto, Natsuko; Kobayashi, Yasuhiro; Udagawa, Nobuyuki; Kaku, Shinsuke; Ueki, Tomokazu; Okazaki, Yasushi; Takahashi, Naoyuki; Suda, Tatsuo.
Affiliation
  • Ochiai N; Research Center for Genomic Medicine, Saitama Medical University, Saitama, 350-1298, Japan.
  • Nakachi Y; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Yokoo T; Research Center for Genomic Medicine, Saitama Medical University, Saitama, 350-1298, Japan.
  • Ichihara T; Research Center for Genomic Medicine, Saitama Medical University, Saitama, 350-1298, Japan.
  • Eriksson T; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Yonemoto Y; Chemistry Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Kato T; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Ogata H; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Fujimoto N; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Kobayashi Y; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Udagawa N; Institutes for Oral Science, Matsumoto Dental University, Nagano, 399-0781, Japan.
  • Kaku S; Department of Biochemistry, Matsumoto Dental University, Nagano, 399-0781, Japan.
  • Ueki T; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Okazaki Y; Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd, Saitama, 331-9530, Japan.
  • Takahashi N; Research Center for Genomic Medicine, Saitama Medical University, Saitama, 350-1298, Japan.
  • Suda T; Center for Genomic and Regenerative Medicine, Juntendo University, Tokyo, 113-8421, Japan.
Commun Biol ; 2: 86, 2019.
Article in En | MEDLINE | ID: mdl-30854478
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Full text: 1 Database: MEDLINE Main subject: Osteoclasts / Bone and Bones / Osteoprotegerin / Cellular Microenvironment / High-Temperature Requirement A Serine Peptidase 1 Type of study: Prognostic_studies Limits: Animals Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Osteoclasts / Bone and Bones / Osteoprotegerin / Cellular Microenvironment / High-Temperature Requirement A Serine Peptidase 1 Type of study: Prognostic_studies Limits: Animals Language: En Year: 2019 Type: Article