Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells.

Shlomchik, M J; Nemazee, D A; Sato, V L; Van Snick, J; Carson, D A; Weigert, M G

Shlomchik, M J; Nemazee, D A; Sato, V L; Van Snick, J; Carson, D A; Weigert, M G.

J Exp Med ; 164(2): 407-27, 1986 Aug 01.

Article in En | MEDLINE | ID: mdl-3088205

Subject(s)

Antibodies, Monoclonal/genetics; B-Lymphocytes/analysis; Immunoglobulin G/immunology; Immunoglobulin M/genetics; Immunoglobulin Variable Region/genetics; Rheumatoid Factor/genetics; Amino Acid Sequence; Animals; Antibodies, Anti-Idiotypic/genetics; Antibody Diversity; B-Lymphocytes/metabolism; Base Sequence; Genes; Immunoglobulin Heavy Chains/genetics; Immunoglobulin Light Chains/genetics; Leukocyte Count; Mice; Mutation

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Full text: 1 Database: MEDLINE Main subject: Rheumatoid Factor / Immunoglobulin G / Immunoglobulin M / Immunoglobulin Variable Region / B-Lymphocytes / Antibodies, Monoclonal Limits: Animals Language: En Year: 1986 Type: Article

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