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The Nonvolatile and Volatile Metabolites of Prangos ferulacea and Their Biological Properties.
Bruno, Maurizio; Ilardi, Vincenzo; Lupidi, Giulio; Quassinti, Luana; Bramucci, Massimo; Fiorini, Dennis; Venditti, Alessandro; Maggi, Filippo.
Affiliation
  • Bruno M; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Parco d'Orleans II, Palermo, Italy.
  • Ilardi V; Department of Earth and Marine Sciences (DISTeM), University of Palermo, Palermo, Italy.
  • Lupidi G; Department of Earth and Marine Sciences (DISTeM), University of Palermo, Palermo, Italy.
  • Quassinti L; School of Pharmacy, University of Camerino, Camerino, Italy.
  • Bramucci M; School of Pharmacy, University of Camerino, Camerino, Italy.
  • Fiorini D; School of Science and Technologies, University of Camerino, Camerino, Italy.
  • Venditti A; Department of Chemistry, University of Rome "La Sapienza", Rome, Italy.
  • Maggi F; School of Pharmacy, University of Camerino, Camerino, Italy.
Planta Med ; 85(11-12): 815-824, 2019 Aug.
Article in En | MEDLINE | ID: mdl-30895566
ABSTRACT
Prangos ferulacea (L.) Lindl. (Fam. Apiaceae), an orophilous species of eastern Mediterranean and western Asia, possesses a number of biological properties that are worthy of exploitation in different fields. Phytochemical investigations revealed the presence of coumarins, prenyl-coumarins, and furano-coumarins as the main constituents of this species, as well as several flavonoids. Among prenyl-coumarins, osthol is a promising apoptotic agent quite selective toward cancer cells. In addition, the essential oils have been extensively investigated, and several chemotypes have been identified. This work reviews the literature on this species published between 1965 and 2018, describes its volatile and nonvolatile metabolites, and outlines its pharmacological effects.
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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Apiaceae Limits: Animals / Humans Language: En Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Apiaceae Limits: Animals / Humans Language: En Year: 2019 Type: Article