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Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform.
Stacey, Glyn N; Andrews, Peter W; Barbaric, Ivana; Boiers, Charlotta; Chandra, Amit; Cossu, Giulio; Csontos, Lynn; Frith, Thomas Jr; Halliwell, Jason A; Hewitt, Zoe; McCall, Mark; Moore, Harry D; Parmar, Malin; Panico, M Beatrice; Pisupati, Venkat; Shichkin, Valentin P; Stacey, Alison R; Tedesco, Francesco S; Thompson, Oliver; Wagey, Ravenska.
Affiliation
  • Stacey GN; International Stem Cell Banking Initiative, 2 High Street, Barley, Hertfordshire SG8 8HZ, UK.
  • Andrews PW; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.
  • Barbaric I; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.
  • Boiers C; Department of Cancer Biology, University College London, London, WC1E 6DD, UK.
  • Chandra A; Cancer Institute, University College London, London, WC1E 6DD, UK.
  • Cossu G; Yposkesi, 91100 Corbiel-Essonnes, France.
  • Csontos L; Division of Cell Matrix Biology & Regenerative Medicine, University of Manchester, M13 9PL, UK.
  • Frith TJ; STEMCELL Technologies, Waterbeach, CB25 9TL, UK.
  • Halliwell JA; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.
  • Hewitt Z; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.
  • McCall M; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.
  • Moore HD; Centre for Biological Engineering, Loughborough University, Loughborough, LE11 3TU, UK.
  • Parmar M; Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, S10 2TN, UK.
  • Panico MB; Developmental & Regenerative Neurobiology, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, S221 84, Sweden.
  • Pisupati V; Lund Stem Cell Center, Lund University, Lund, S221 84, Sweden.
  • Shichkin VP; Medicines & Healthcare products Regulatory Agency, London, E14 4PU, UK.
  • Stacey AR; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Tedesco FS; Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, CB2 0PY, UK.
  • Thompson O; Research Centre of Immunology & Biomedical Technologies, Open International University of Human Development Ukraine, Kyiv 03115, Ukraine.
  • Wagey R; Bienta Ltd, 78 Chervonotkatska Str., Kyiv 02094, Ukraine.
Regen Med ; 14(3): 243-255, 2019 03.
Article in En | MEDLINE | ID: mdl-30938271
Human stem cells have the potential to transform medicine. However, hurdles remain to ensure that manufacturing processes produce safe and effective products. A thorough understanding of the biological processes occurring during manufacture is fundamental to assuring these qualities and thus, their acceptability to regulators and clinicians. Leaders in both human pluripotent and somatic stem cells, were brought together with experts in clinical translation, biomanufacturing and regulation, to discuss key issues in assuring appropriate manufacturing conditions for delivery of effective and safe products from these cell types. This report summarizes the key issues discussed and records consensus reached by delegates and emphasizes the need for accurate language and nomenclature in the scientific discourse around stem cells.
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Full text: 1 Database: MEDLINE Main subject: Cell Differentiation / Cell Culture Techniques / Pluripotent Stem Cells / Regenerative Medicine / Adult Stem Cells / Cell- and Tissue-Based Therapy Limits: Humans Language: En Year: 2019 Type: Article

Full text: 1 Database: MEDLINE Main subject: Cell Differentiation / Cell Culture Techniques / Pluripotent Stem Cells / Regenerative Medicine / Adult Stem Cells / Cell- and Tissue-Based Therapy Limits: Humans Language: En Year: 2019 Type: Article