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Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5.
Quinn, Peter M; Buck, Thilo M; Mulder, Aat A; Ohonin, Charlotte; Alves, C Henrique; Vos, Rogier M; Bialecka, Monika; van Herwaarden, Tessa; van Dijk, Elon H C; Talib, Mays; Freund, Christian; Mikkers, Harald M M; Hoeben, Rob C; Goumans, Marie-José; Boon, Camiel J F; Koster, Abraham J; Chuva de Sousa Lopes, Susana M; Jost, Carolina R; Wijnholds, Jan.
Affiliation
  • Quinn PM; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Buck TM; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Mulder AA; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Ohonin C; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Alves CH; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Vos RM; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), 1105 BA Amsterdam, The Netherlands.
  • Bialecka M; Department of Anatomy and Embryology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • van Herwaarden T; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • van Dijk EHC; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Talib M; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Freund C; Department of Anatomy and Embryology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Mikkers HMM; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Hoeben RC; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Goumans MJ; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Boon CJF; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands; Department of Ophthalmology, Amsterdam University Medical Centers, Academic Medical Center, University of Amsterdam, 1000 AE Amsterdam, The Netherlands.
  • Koster AJ; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Chuva de Sousa Lopes SM; Department of Anatomy and Embryology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Jost CR; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands.
  • Wijnholds J; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZA Leiden, The Netherlands; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), 1105 BA Amsterdam, The Netherlands. Electronic address: j.wijnholds@lumc.nl.
Stem Cell Reports ; 12(5): 906-919, 2019 05 14.
Article in En | MEDLINE | ID: mdl-30956116
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Full text: 1 Database: MEDLINE Main subject: Retina / Carrier Proteins / Organoids / Photoreceptor Cells, Vertebrate / Eye Proteins / Induced Pluripotent Stem Cells / Ependymoglial Cells / Membrane Proteins / Nerve Tissue Proteins Limits: Adult / Female / Humans / Pregnancy Language: En Year: 2019 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Retina / Carrier Proteins / Organoids / Photoreceptor Cells, Vertebrate / Eye Proteins / Induced Pluripotent Stem Cells / Ependymoglial Cells / Membrane Proteins / Nerve Tissue Proteins Limits: Adult / Female / Humans / Pregnancy Language: En Year: 2019 Type: Article