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A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2Rßγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors.
Bentebibel, Salah-Eddine; Hurwitz, Michael E; Bernatchez, Chantale; Haymaker, Cara; Hudgens, Courtney W; Kluger, Harriet M; Tetzlaff, Michael T; Tagliaferri, Mary A; Zalevsky, Jonathan; Hoch, Ute; Fanton, Christie; Aung, Sandra; Hwu, Patrick; Curti, Brendan D; Tannir, Nizar M; Sznol, Mario; Diab, Adi.
Affiliation
  • Bentebibel SE; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hurwitz ME; Yale School of Medicine, New Haven, Connecticut.
  • Bernatchez C; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Haymaker C; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hudgens CW; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kluger HM; Yale School of Medicine, New Haven, Connecticut.
  • Tetzlaff MT; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tagliaferri MA; Nektar Therapeutics, San Francisco, California.
  • Zalevsky J; Nektar Therapeutics, San Francisco, California.
  • Hoch U; Nektar Therapeutics, San Francisco, California.
  • Fanton C; Nektar Therapeutics, San Francisco, California.
  • Aung S; Nektar Therapeutics, San Francisco, California.
  • Hwu P; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Curti BD; Providence Cancer Institute and Earle A. Chiles Research Institute, Portland, Oregon.
  • Tannir NM; The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Sznol M; Yale School of Medicine, New Haven, Connecticut.
  • Diab A; The University of Texas MD Anderson Cancer Center, Houston, Texas. adiab@mdanderson.org.
Cancer Discov ; 9(6): 711-721, 2019 06.
Article in En | MEDLINE | ID: mdl-30988166
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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Signal Transduction / Interleukin-2 / Interleukin-2 Receptor alpha Subunit / Neoplasms Type of study: Clinical_trials / Etiology_studies Limits: Humans Language: En Year: 2019 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Signal Transduction / Interleukin-2 / Interleukin-2 Receptor alpha Subunit / Neoplasms Type of study: Clinical_trials / Etiology_studies Limits: Humans Language: En Year: 2019 Type: Article