ABSTRACT
PURPOSE:
To study the effect of
mandibulectomy with soft
tissue reconstruction on
quality of life (QOL) and functions of
speech and
swallowing.
METHODOLOGY:
Quality of life of 66
patients was evaluated by using EORTC QLQ-C30 and EORTC-HN35
questionnaires.
Speech was evaluated objectively by Dr.
Speech software version 4 and subjectively by a single
speech therapist along with
swallowing.
Patients were evaluated preoperatively and 6 months
after treatment.
RESULTS:
Out of 66
patients, 57 followed up postoperatively. Comparison of preoperative and postoperative QOL,
speech, and
swallowing was done by using paired 't' test or Wilcoxon signed-rank test as per distribution. When evaluated by EORTC QLQ-C30 and EORTC-HN35, statistically significant difference was found in the domains of physical function,
fatigue,
nausea-
vomiting,
dyspnea and
appetite loss,
pain,
nutrition,
swallowing speech and dry
mouth. Significant difference was found in
speech (maximum intensity) and most of the domains of
swallowing.
CONCLUSION:
In EORTC QLQ-C30
questionnaire, all functional
scales showed deterioration with maximum in physical function. Symptom
scales showed worsening but significant improvement was found in
pain when evaluated by EORTC-HN35. However, the
global health status/QL was found to be improved marginally.
