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Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity.
Punchi Hewage, Achala N D; Yao, Huili; Nammalwar, Baskar; Gnanasekaran, Krishna Kumar; Lovell, Scott; Bunce, Richard A; Eshelman, Kate; Phaniraj, Sahishna M; Lee, Molly M; Peterson, Blake R; Battaile, Kevin P; Reitz, Allen B; Rivera, Mario.
Affiliation
  • Punchi Hewage AND; Department of Chemistry , University of Kansas , 2030 Becker Drive , Lawrence , Kansas 66047 , United States.
  • Yao H; Department of Chemistry , Louisiana State University , 229A Choppin Hall , Baton Rouge , Louisiana 70803 , United States.
  • Nammalwar B; Department of Chemistry , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.
  • Gnanasekaran KK; Department of Chemistry , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.
  • Lovell S; Protein Structure Laboratory , University of Kansas , 2034 Becker Drive , Lawrence , Kansas 66047 , United States.
  • Bunce RA; Department of Chemistry , Oklahoma State University , Stillwater , Oklahoma 74078 , United States.
  • Eshelman K; Department of Chemistry , University of Kansas , 2030 Becker Drive , Lawrence , Kansas 66047 , United States.
  • Phaniraj SM; Department of Medicinal Chemistry , University of Kansas , 2034 Becker Drive , Lawrence , Kansas 66047 , United States.
  • Lee MM; Department of Medicinal Chemistry , University of Kansas , 2034 Becker Drive , Lawrence , Kansas 66047 , United States.
  • Peterson BR; Department of Medicinal Chemistry , University of Kansas , 2034 Becker Drive , Lawrence , Kansas 66047 , United States.
  • Battaile KP; IMCA-CAT , Hauptman Woodward Medical Research Institute , 9700 South Cass Avenue, Building 435A , Argonne , Illinois 60439 , United States.
  • Reitz AB; Fox Chase Chemical Diversity Center, Inc. , 3805 Old Easton Road , Doylestown , Pennsylvania 18902 , United States.
  • Rivera M; Department of Chemistry , Louisiana State University , 229A Choppin Hall , Baton Rouge , Louisiana 70803 , United States.
J Am Chem Soc ; 141(20): 8171-8184, 2019 05 22.
Article in En | MEDLINE | ID: mdl-31038945
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Full text: 1 Database: MEDLINE Main subject: Phthalimides / Pseudomonas aeruginosa / Bacterial Proteins / Fluoroquinolones / Protein Multimerization / Anti-Bacterial Agents Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Phthalimides / Pseudomonas aeruginosa / Bacterial Proteins / Fluoroquinolones / Protein Multimerization / Anti-Bacterial Agents Language: En Year: 2019 Type: Article