Your browser doesn't support javascript.
loading
News and meta-analysis regarding anti-Beta 2 glycoprotein I antibodies and their determination.
Bettacchioli, Eléonore; Nafai, Salma; Renaudineau, Yves.
Affiliation
  • Bettacchioli E; Laboratory of Immunology and Immunotherapy, CHU, Brest, France. Electronic address: eleonore.bettacchioli@chu-brest.fr.
  • Nafai S; Laboratory of Immunology and Immunotherapy, CHU, Brest, France.
  • Renaudineau Y; Laboratory of Immunology and Immunotherapy, CHU, Brest, France; UMR1227, Lymphocytes B et Autoimmunité, Université de Brest, INSERM, CHU de Brest, Brest, France. Electronic address: yves.renaudineau@univ-brest.fr.
Clin Immunol ; 205: 106-115, 2019 08.
Article in En | MEDLINE | ID: mdl-31173887
ABSTRACT
Recent advances allow us to propose antibodies targeting beta-2-glycoprotein I (ß2-GPI) as the most specific antibodies associated with anti-phospholipid syndrome (APS). Therefore, there is now a crucial need for powerful biological assays to adequately monitor them. It is well established that these antibodies recognize mainly cryptic epitopes, which requires a great deal of consideration in the choice of laboratory tests to identify these antibodies. To this end, an update on the pathophysiological role of ß2-GPI and a meta-analysis were conducted providing an overview of the current progress towards anti-ß2-GPI detection.
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Antiphospholipid Syndrome / Antibodies, Antiphospholipid / Beta 2-Glycoprotein I Type of study: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limits: Humans Language: En Year: 2019 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Antiphospholipid Syndrome / Antibodies, Antiphospholipid / Beta 2-Glycoprotein I Type of study: Diagnostic_studies / Prognostic_studies / Systematic_reviews Limits: Humans Language: En Year: 2019 Type: Article