Mapping of the structural gene for the second component of complement with respect to the human major histocompatibility complex.
Am J Hum Genet
; 31(1): 35-41, 1979 Jan.
Article
in En
| MEDLINE
| ID: mdl-312013
ABSTRACT
Families have been HLA typed, and allotypes of the second component of complement and properdin factor B determined. The lod score for the C2 structural gene and HLA-B from the study of 11 families and 55 informative meioses was 14.39 at maximum likelihood estimate of the recombination fraction of .02. This is related to other estimates of the distance between these two genes. The relative kinetic activities of the C2 allotypes were studied and no differences were demonstrated. No crossovers between Bf and C2 were observed.
Full text:
1
Database:
MEDLINE
Main subject:
Complement C2
/
Chromosome Mapping
/
Genes
/
Major Histocompatibility Complex
Limits:
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
En
Year:
1979
Type:
Article