Microsatellite instability diagnosis using the fully automated Idylla platform: feasibility study of an in-house rapid molecular testing ancillary to immunohistochemistry in pathology laboratories.

Samaison, Laura; Grall, Mélanie; Staroz, Frédéric; Uguen, Arnaud

Samaison, Laura; Grall, Mélanie; Staroz, Frédéric; Uguen, Arnaud.

Affiliation

Samaison L; Ouest Pathologie, Quimper, France.
Grall M; Ouest Pathologie, Quimper, France.
Staroz F; Ouest Pathologie, Quimper, France.
Uguen A; Pathology, CHRU Brest, Brest, France arnaud.uguen@chu-brest.fr.

J Clin Pathol ; 72(12): 830-835, 2019 Dec.

Article in En | MEDLINE | ID: mdl-31235541

Subject(s)

Biomarkers, Tumor/genetics; Microsatellite Instability; Molecular Diagnostic Techniques/instrumentation; Neoplasms/genetics; Adult; Aged; Automation, Laboratory; Biomarkers, Tumor/analysis; Clinical Decision-Making; Feasibility Studies; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasms/chemistry; Neoplasms/pathology; Neoplasms/therapy; Predictive Value of Tests; Prognosis; Retrospective Studies; Workflow

Key words

Idylla; colorectal cancer; immunohistochemistry; microsatellite instability; mismatch repair deficiency

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Full text: 1 Database: MEDLINE Main subject: Biomarkers, Tumor / Molecular Diagnostic Techniques / Microsatellite Instability / Neoplasms Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2019 Type: Article

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