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One-step synthesis of methylene-bridged bis-carbazole and evaluation of its antitumor activity and G-quadruplex DNA binding property.
Li, Gang; Tang, Haodong; Liu, Chuanfeng; Liao, Xiaoyu; Li, Sicong; Shu, Zhengning; Yu, Hui; Yang, Peng.
Affiliation
  • Li G; Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Tang H; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Liu C; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Liao X; Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Li S; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Shu Z; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Yu H; School of Textile Materials and Engineering, Wuyi University, Jiangmen 529020, China.
  • Yang P; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China; Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: yangpeng@syphu.edu.cn.
Bioorg Chem ; 90: 103074, 2019 09.
Article in En | MEDLINE | ID: mdl-31255989
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Full text: 1 Database: MEDLINE Main subject: DNA / Carbazoles / G-Quadruplexes / Neoplasms / Antineoplastic Agents Type of study: Evaluation_studies Limits: Humans Language: En Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: DNA / Carbazoles / G-Quadruplexes / Neoplasms / Antineoplastic Agents Type of study: Evaluation_studies Limits: Humans Language: En Year: 2019 Type: Article