Protective Effects of Timosaponin AIII against UVB-Radiation Induced Inflammation and DNA Injury in Human Epidermal Keratinocytes.

Kim, Ki Mo; Im, A-Rang; Park, Se Kyu; Shin, Hyoung Seok; Chae, Sung-Wook

Kim, Ki Mo; Im, A-Rang; Park, Se Kyu; Shin, Hyoung Seok; Chae, Sung-Wook.

Affiliation

Kim KM; Herbal Medicine Division, Korea Institute of Oriental Medicine.
Im AR; Department of Korean Life Science and Technology, University of Science and Technology.
Park SK; Herbal Medicine Division, Korea Institute of Oriental Medicine.
Shin HS; Hansolbio Company.
Chae SW; Hansolbio Company.

Biol Pharm Bull ; 42(9): 1524-1531, 2019 Sep 01.

Article in En | MEDLINE | ID: mdl-31270288

Subject(s)

Anti-Inflammatory Agents/pharmacology; Keratinocytes/drug effects; Keratinocytes/radiation effects; Saponins/pharmacology; Steroids/pharmacology; Ultraviolet Rays; Cell Survival/drug effects; Cell Survival/radiation effects; Cells, Cultured; Cyclooxygenase 2/genetics; DNA Damage; Humans; Keratinocytes/metabolism; Matrix Metalloproteinase 9/genetics; Mitogen-Activated Protein Kinases/metabolism; NF-kappa B/metabolism; Radiation-Protective Agents/pharmacology; Signal Transduction/drug effects; Transcription Factor AP-1/metabolism

Key words

Timosaponin AIII; UVB; human epidermal keratinocyte; inflammation; matrix metalloproteinase-9; photo-damage

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Saponins / Steroids / Ultraviolet Rays / Keratinocytes / Anti-Inflammatory Agents Limits: Humans Language: En Year: 2019 Type: Article

Fulltext

XML

PubMed Links

Search on Google