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Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.
Rehm, Salome R T; Smirnova, Natalia F; Morrone, Carmela; Götzfried, Jessica; Feuchtinger, Annette; Pedersen, John; Korkmaz, Brice; Yildirim, Ali Önder; Jenne, Dieter E.
Affiliation
  • Rehm SRT; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease (iLBD), Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University (LMU), Munich, 81377, Germany.
  • Smirnova NF; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease (iLBD), Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University (LMU), Munich, 81377, Germany.
  • Morrone C; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease (iLBD), Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University (LMU), Munich, 81377, Germany.
  • Götzfried J; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease (iLBD), Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University (LMU), Munich, 81377, Germany.
  • Feuchtinger A; Research Unit Analytical Pathology, Institute of Pathology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Pedersen J; Neuprozyme Therapeutics and Unizyme Laboratories A/S, Agern Allé, DK2970, Hoersholm, Denmark.
  • Korkmaz B; INSERM U-1100, "Centre d'Etude des Pathologies Respiratoires (CEPR)", and Université de Tours, Tours, France.
  • Yildirim AÖ; Comprehensive Pneumology Center (CPC-M), Institute of Lung Biology and Disease (iLBD), Helmholtz Zentrum München and University Hospital of the Ludwig-Maximilians University (LMU), Munich, 81377, Germany.
  • Jenne DE; German Center for Lung Research, Munich, 81377, Germany.
Sci Rep ; 9(1): 9925, 2019 07 09.
Article in En | MEDLINE | ID: mdl-31289357
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Full text: 1 Database: MEDLINE Main subject: Premedication / Protease Inhibitors / Lung Transplantation / Cathepsin C / Primary Graft Dysfunction / Inflammation Type of study: Etiology_studies Limits: Animals Language: En Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Premedication / Protease Inhibitors / Lung Transplantation / Cathepsin C / Primary Graft Dysfunction / Inflammation Type of study: Etiology_studies Limits: Animals Language: En Year: 2019 Type: Article