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The STING activator c-di-AMP exerts superior adjuvant properties than the formulation poly(I:C)/CpG after subcutaneous vaccination with soluble protein antigen or DEC-205-mediated antigen targeting to dendritic cells.
Volckmar, Julia; Knop, Laura; Stegemann-Koniszewski, Sabine; Schulze, Kai; Ebensen, Thomas; Guzmán, Carlos A; Bruder, Dunja.
Affiliation
  • Volckmar J; Infection Immunology Group, Institute of Medical Microbiology, Infection Control and Prevention, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany; Immune Regulation Group, Helmholtz Centre for Infection Resea
  • Knop L; Infection Immunology Group, Institute of Medical Microbiology, Infection Control and Prevention, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany; Immune Regulation Group, Helmholtz Centre for Infection Resea
  • Stegemann-Koniszewski S; Infection Immunology Group, Institute of Medical Microbiology, Infection Control and Prevention, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany; Immune Regulation Group, Helmholtz Centre for Infection Resea
  • Schulze K; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124 Braunschweig, Germany.
  • Ebensen T; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124 Braunschweig, Germany.
  • Guzmán CA; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstraße 7, 38124 Braunschweig, Germany.
  • Bruder D; Infection Immunology Group, Institute of Medical Microbiology, Infection Control and Prevention, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany; Immune Regulation Group, Helmholtz Centre for Infection Resea
Vaccine ; 37(35): 4963-4974, 2019 08 14.
Article in En | MEDLINE | ID: mdl-31320219
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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Dinucleoside Phosphates / Antigens, CD / Minor Histocompatibility Antigens / Adjuvants, Immunologic / Receptors, Cell Surface / Lectins, C-Type Limits: Animals Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Dinucleoside Phosphates / Antigens, CD / Minor Histocompatibility Antigens / Adjuvants, Immunologic / Receptors, Cell Surface / Lectins, C-Type Limits: Animals Language: En Year: 2019 Type: Article