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NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.
Ohata, Hirokazu; Shiokawa, Daisuke; Obata, Yuuki; Sato, Ai; Sakai, Hiroaki; Fukami, Mayu; Hara, Wakako; Taniguchi, Hirokazu; Ono, Masaya; Nakagama, Hitoshi; Okamoto, Koji.
Affiliation
  • Ohata H; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Shiokawa D; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Obata Y; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Sato A; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Sakai H; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Fukami M; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Hara W; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Taniguchi H; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Ono M; Department of Clinical Proteomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Nakagama H; National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Okamoto K; Division of Cancer Differentiation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address: kojokamo@ncc.go.jp.
Cell Rep ; 28(5): 1282-1295.e8, 2019 07 30.
Article in En | MEDLINE | ID: mdl-31365870
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Colonic Neoplasms / Calgranulin B / Mechanistic Target of Rapamycin Complex 1 / NADPH Oxidase 1 / Neoplasm Proteins Limits: Animals / Humans / Male Language: En Year: 2019 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Colonic Neoplasms / Calgranulin B / Mechanistic Target of Rapamycin Complex 1 / NADPH Oxidase 1 / Neoplasm Proteins Limits: Animals / Humans / Male Language: En Year: 2019 Type: Article