ABSTRACT
BACKGROUND:
The principle
treatment for retroperitoneal
liposarcoma is surgical resection, however there are many cases of
recurrence. In addition to local
recurrence, retroperitoneal
liposarcoma, particularly
dedifferentiated liposarcoma is known to occasionally cause
lung metastases. CASE
REPORT A 72-year-old
woman with a
diagnosis of retroperitoneal
liposarcoma and probable right upper lobe early pulmonary
adenocarcinoma underwent sequential local
tumor resection and right upper lobectomy. Twenty months after
liposarcoma resection, a computed
tomography (CT) scan of the
chest revealed a nodule located in the left lower lobe. A CT-guided
biopsy was performed and she was subsequently diagnosed with pulmonary
metastasis from retroperitoneal
liposarcoma. The nodule enlarged chronologically, however a left lower lobectomy could not be performed because respiratory function after the right upper lobectomy was not sufficient. Therefore, in order to preserve the left superior segment (S6), the basal segments (S8+S9+S10) were resected. Seven months after the
surgery, she is living a
self-reliant
life without
recurrence of
liposarcoma.
CONCLUSION:
Here we have reported a case of pulmonary
metastasis from retroperitoneal
liposarcoma following limited
surgery. In cases where respiratory function is limited, lower lobe
segmentectomy can be an effective
treatment. For the
treatment of a single pulmonary
metastasis from retroperitoneal
liposarcoma,
metastasectomy was considered to be effective as long as no local
recurrence was seen after initial primary
tumor resection.