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Comparative pharmacokinetic and biodistribution study of two distinct squalene-containing oil-in-water emulsion adjuvants in H5N1 influenza vaccines.
Tegenge, Million A; Von Tungeln, Linda S; Anderson, Steven A; Mitkus, Robert J; Vanlandingham, Michelle M; Forshee, Richard A; Beland, Frederick A.
Affiliation
  • Tegenge MA; Office of Biostatistics & Epidemiology, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, 20993, USA. Electronic address: million.tegenge@fda.hhs.gov.
  • Von Tungeln LS; Division of Biochemical Toxicology, National Center for Toxicological Research, FDA, Jefferson, AR, 72079, USA.
  • Anderson SA; Office of Biostatistics & Epidemiology, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, 20993, USA.
  • Mitkus RJ; Office of Biostatistics & Epidemiology, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, 20993, USA; Current Address: BASF Corporation, 26 Davis Drive, Durham, NC, 27709, USA.
  • Vanlandingham MM; Division of Biochemical Toxicology, National Center for Toxicological Research, FDA, Jefferson, AR, 72079, USA.
  • Forshee RA; Office of Biostatistics & Epidemiology, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, 20993, USA.
  • Beland FA; Division of Biochemical Toxicology, National Center for Toxicological Research, FDA, Jefferson, AR, 72079, USA.
Regul Toxicol Pharmacol ; 108: 104436, 2019 Nov.
Article in En | MEDLINE | ID: mdl-31381939
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Full text: 1 Database: MEDLINE Main subject: Polysorbates / Squalene / Influenza Vaccines / Adjuvants, Immunologic / Alpha-Tocopherol / Influenza A Virus, H5N1 Subtype Limits: Animals Language: En Year: 2019 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Polysorbates / Squalene / Influenza Vaccines / Adjuvants, Immunologic / Alpha-Tocopherol / Influenza A Virus, H5N1 Subtype Limits: Animals Language: En Year: 2019 Type: Article