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Clinical Efficacy and Tumor Microenvironment Influence in a Dose-Escalation Study of Anti-CD19 Chimeric Antigen Receptor T Cells in Refractory B-Cell Non-Hodgkin's Lymphoma.
Yan, Zi-Xun; Li, Li; Wang, Wen; OuYang, Bin-Shen; Cheng, Shu; Wang, Li; Wu, Wen; Xu, Peng-Peng; Muftuoglu, Muharrem; Hao, Ming; Yang, Su; Zhang, Mu-Chen; Zheng, Zhong; Li, James; Zhao, Wei-Li.
Affiliation
  • Yan ZX; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Li L; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Wang W; JW Therapeutics, Shanghai, China.
  • OuYang BS; Department of Pathology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Cheng S; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Wang L; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Wu W; Pôle de Recherches Sino-Français en Science du Vivant et Génomique, Laboratory of Molecular Pathology, Shanghai, China.
  • Xu PP; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Muftuoglu M; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Hao M; Department of Leukemia, University of Texas - MD Anderson Cancer Center, Houston, Texas.
  • Yang S; JW Therapeutics, Shanghai, China.
  • Zhang MC; JW Therapeutics, Shanghai, China.
  • Zheng Z; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Li J; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Zhao WL; JW Therapeutics, Shanghai, China.
Clin Cancer Res ; 25(23): 6995-7003, 2019 12 01.
Article in En | MEDLINE | ID: mdl-31444250
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Full text: 1 Database: MEDLINE Main subject: Immunotherapy, Adoptive / Lymphoma, B-Cell / Antigens, CD19 / Tumor Microenvironment / Immunotherapy / Antibodies, Monoclonal / Neoplasm Recurrence, Local Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Immunotherapy, Adoptive / Lymphoma, B-Cell / Antigens, CD19 / Tumor Microenvironment / Immunotherapy / Antibodies, Monoclonal / Neoplasm Recurrence, Local Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2019 Type: Article