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DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.
Sustmann, Claudio; Dickopf, Steffen; Regula, Jörg T; Kettenberger, Hubert; Mølhøj, Michael; Gassner, Christian; Weininger, Diana; Fenn, Sebastian; Manigold, Tobias; Kling, Lothar; Künkele, Klaus-Peter; Schwaiger, Manfred; Bossenmaier, Birgit; Griese, Julia J; Hopfner, Karl-Peter; Graff-Meyer, Alexandra; Stahlberg, Henning; Ringler, Philippe; Lauer, Matthias E; Brinkmann, Ulrich; Schaefer, Wolfgang; Klein, Christian.
Affiliation
  • Sustmann C; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Dickopf S; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Regula JT; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Kettenberger H; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Mølhøj M; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Gassner C; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Weininger D; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Fenn S; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Manigold T; Roche Pharma Research and Early Development (pRED), Discovery Oncology, Roche Innovation Center Basel , Basel , Switzerland.
  • Kling L; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Künkele KP; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Schwaiger M; Roche Pharma Research and Early Development (pRED), Discovery Oncology, Roche Innovation Center Basel , Basel , Switzerland.
  • Bossenmaier B; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Griese JJ; Gene Center and Department of Biochemistry, Ludwig-Maximilians-University , Munich , Germany.
  • Hopfner KP; Gene Center and Department of Biochemistry, Ludwig-Maximilians-University , Munich , Germany.
  • Graff-Meyer A; Center for Cellular Imaging and Nanoanalytics, Biozentrum, University of Basel , Basel , Switzerland.
  • Stahlberg H; Center for Cellular Imaging and Nanoanalytics, Biozentrum, University of Basel , Basel , Switzerland.
  • Ringler P; Center for Cellular Imaging and Nanoanalytics, Biozentrum, University of Basel , Basel , Switzerland.
  • Lauer ME; Roche Pharma Research and Early Development (pRED), Small Molecule Research, Roche Innovation Center Basel , Basel , Switzerland.
  • Brinkmann U; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Schaefer W; Roche Pharma Research and Early Development (pRED), Large Molecule Research (LMR), Roche Innovation Center Munich , Penzberg , Germany.
  • Klein C; Roche Pharma Research and Early Development (pRED), Discovery Oncology, Roche Innovation Center Zurich , Schlieren , Switzerland.
MAbs ; 11(8): 1402-1414, 2019.
Article in En | MEDLINE | ID: mdl-31526159
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin G / Immunoglobulin Fc Fragments / Antibodies, Bispecific / Antibodies, Monoclonal / Antibody-Dependent Cell Cytotoxicity Limits: Humans Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin G / Immunoglobulin Fc Fragments / Antibodies, Bispecific / Antibodies, Monoclonal / Antibody-Dependent Cell Cytotoxicity Limits: Humans Language: En Year: 2019 Type: Article