Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

Tam, Susan H; McCarthy, Stephen G; Armstrong, Anthony A; Somani, Sandeep; Wu, Sheng-Jiun; Liu, Xuesong; Gervais, Alexis; Ernst, Robin; Saro, Dorina; Decker, Rose; Luo, Jinquan; Gilliland, Gary L; Chiu, Mark L; Scallon, Bernard J

Tam, Susan H; McCarthy, Stephen G; Armstrong, Anthony A; Somani, Sandeep; Wu, Sheng-Jiun; Liu, Xuesong; Gervais, Alexis; Ernst, Robin; Saro, Dorina; Decker, Rose; Luo, Jinquan; Gilliland, Gary L; Chiu, Mark L; Scallon, Bernard J.

Affiliation

Tam SH; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. susanhtam@gmail.com.
McCarthy SG; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. sgmcc0711@gmail.com.
Armstrong AA; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. aarmst12@its.jnj.com.
Somani S; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. ssomani@its.jnj.com.
Wu SJ; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. swu4@its.jnj.com.
Liu X; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. xliu8@its.jnj.com.
Gervais A; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. agervais@its.jnj.com.
Ernst R; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. rernst2@its.jnj.com.
Saro D; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. dsaro@its.jnj.com.
Decker R; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. rdecker5@its.jnj.com.
Luo J; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. jluo@its.jnj.com.
Gilliland GL; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. ggillila@its.jnj.com.
Chiu ML; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. mchiu@its.jnj.com.
Scallon BJ; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Ambler, PA 19477, USA. bhscallon@gmail.com.