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Acne: Transient Arrest in the Homeostatic Host-Microbiota Dialog?
Szegedi, Andrea; Dajnoki, Zsolt; Bíró, Tamás; Kemény, Lajos; Törocsik, Dániel.
Affiliation
  • Szegedi A; Division of Dermatological Allergology, Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary. Electronic address: aszegedi@med.unideb.hu.
  • Dajnoki Z; Division of Dermatological Allergology, Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Bíró T; Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
  • Kemény L; Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary; MTA-SZTE Dermatological Research Group, Szeged, Hungary.
  • Törocsik D; Division of Dermatological Allergology, Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Trends Immunol ; 40(10): 873-876, 2019 10.
Article in En | MEDLINE | ID: mdl-31564639
ABSTRACT
We propose that acne vulgaris represents a naturally developing, transient inflammatory interaction of adolescent facial skin with its new microbial/chemical milieu (Cutibacterium acnes, sebum), replacing a state of previous childhood skin homeostasis. This concept might explain why acne is characterized by strong regional and age specificity, prevalent occurrence, and resolution.
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Full text: 1 Database: MEDLINE Main subject: Propionibacterium acnes / Host-Pathogen Interactions / Microbiota / Homeostasis Limits: Humans Language: En Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Propionibacterium acnes / Host-Pathogen Interactions / Microbiota / Homeostasis Limits: Humans Language: En Year: 2019 Type: Article