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The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
Deora, Vandana; Lee, John D; Albornoz, Eduardo A; McAlary, Luke; Jagaraj, Cyril J; Robertson, Avril A B; Atkin, Julie D; Cooper, Matthew A; Schroder, Kate; Yerbury, Justin J; Gordon, Richard; Woodruff, Trent M.
Affiliation
  • Deora V; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, St. Lucia, Queensland, Australia.
  • Lee JD; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, St. Lucia, Queensland, Australia.
  • Albornoz EA; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia.
  • McAlary L; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, St. Lucia, Queensland, Australia.
  • Jagaraj CJ; Institute for Molecular Bioscience, and Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Queensland, Australia.
  • Robertson AAB; School of Chemistry and Molecular Biosciences, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.
  • Atkin JD; Illawarra Health and Medical Institute, University of Wollongong, Wollongong, New South Wales, Australia.
  • Cooper MA; Faculty of Medicine and Health Sciences, Department of Biomedical Sciences, Centre for MND Research, Macquarie University, New South Wales, Australia.
  • Schroder K; Institute for Molecular Bioscience, and Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Queensland, Australia.
  • Yerbury JJ; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Queensland, Australia.
  • Gordon R; Faculty of Medicine and Health Sciences, Department of Biomedical Sciences, Centre for MND Research, Macquarie University, New South Wales, Australia.
  • Woodruff TM; Institute for Molecular Bioscience, and Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Queensland, Australia.
Glia ; 68(2): 407-421, 2020 02.
Article in En | MEDLINE | ID: mdl-31596526
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Full text: 1 Database: MEDLINE Main subject: Microglia / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Amyotrophic Lateral Sclerosis Limits: Animals / Humans Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Microglia / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Amyotrophic Lateral Sclerosis Limits: Animals / Humans Language: En Year: 2020 Type: Article