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The α4ß7 blockade with vedolizumab is effective in prevention of graft vs. host disease using a xenogeneic mouse model.
Palaniyandi, Senthilnathan; Kumari, Reena; Strattan, Ethan; Huang, Timothy; Du, Jing; Hakim, Natalya; Kesler, Melissa V; Hildebrandt, Gerhard C.
Affiliation
  • Palaniyandi S; Department of Internal Medicine, Markey Cancer Center, Division of Hematology & Blood and Marrow Transplantation, University of Kentucky, Lexington, Kentucky.
  • Kumari R; Department of Internal Medicine, Markey Cancer Center, Division of Hematology & Blood and Marrow Transplantation, University of Kentucky, Lexington, Kentucky.
  • Strattan E; Department of Internal Medicine, Markey Cancer Center, Division of Hematology & Blood and Marrow Transplantation, University of Kentucky, Lexington, Kentucky.
  • Huang T; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, Kentucky.
  • Du J; Department of Internal Medicine, Markey Cancer Center, Division of Hematology & Blood and Marrow Transplantation, University of Kentucky, Lexington, Kentucky.
  • Hakim N; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky.
  • Kesler MV; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky.
  • Hildebrandt GC; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, Kentucky.
Am J Hematol ; 95(2): E39-E41, 2020 02.
Article in En | MEDLINE | ID: mdl-31724186
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Full text: 1 Database: MEDLINE Main subject: Integrin alpha4 / Integrin beta Chains / Antibodies, Monoclonal, Humanized / Graft vs Host Disease Limits: Animals / Humans Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Integrin alpha4 / Integrin beta Chains / Antibodies, Monoclonal, Humanized / Graft vs Host Disease Limits: Animals / Humans Language: En Year: 2020 Type: Article