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A heterodimer of evolved designer-recombinases precisely excises a human genomic DNA locus.
Lansing, Felix; Paszkowski-Rogacz, Maciej; Schmitt, Lukas Theo; Schneider, Paul Martin; Rojo Romanos, Teresa; Sonntag, Jan; Buchholz, Frank.
Affiliation
  • Lansing F; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
  • Paszkowski-Rogacz M; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
  • Schmitt LT; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
  • Schneider PM; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
  • Rojo Romanos T; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
  • Sonntag J; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
  • Buchholz F; Medical Faculty and University Hospital Carl Gustav Carus, UCC Section Medical Systems Biology, TU Dresden, 01307 Dresden, Germany.
Nucleic Acids Res ; 48(1): 472-485, 2020 01 10.
Article in En | MEDLINE | ID: mdl-31745551
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Full text: 1 Database: MEDLINE Main subject: Chromosomes, Human, Pair 7 / Base Sequence / Genome, Human / Sequence Deletion / DNA Nucleotidyltransferases / Gene Editing Limits: Humans Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Chromosomes, Human, Pair 7 / Base Sequence / Genome, Human / Sequence Deletion / DNA Nucleotidyltransferases / Gene Editing Limits: Humans Language: En Year: 2020 Type: Article