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Matteucinol, isolated from Miconia chamissois, induces apoptosis in human glioblastoma lines via the intrinsic pathway and inhibits angiogenesis and tumor growth in vivo.
Silva, Ana Gabriela; Silva, Viviane Aline O; Oliveira, Renato J S; de Rezende, Allisson Rodrigues; Chagas, Rafael César Russo; Pimenta, Lúcia Pinheiro Santos; Romão, Wanderson; Santos, Hélio Batista; Thomé, Ralph Gruppi; Reis, Rui Manuel; de Azambuja Ribeiro, Rosy Iara Maciel.
Affiliation
  • Silva AG; Experimental Pathology Laboratory, Federal University of São João del Rei, 400, Sebastião Gonçalves Coelho- Chanadour, Divinópolis, MG, 35501-296, Brazil.
  • Silva VAO; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, 14784-400, Brazil.
  • Oliveira RJS; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, 14784-400, Brazil.
  • de Rezende AR; State University of Minas Gerais, Ituiutaba, MG, 38302-192, Brazil.
  • Chagas RCR; Experimental Pathology Laboratory, Federal University of São João del Rei, 400, Sebastião Gonçalves Coelho- Chanadour, Divinópolis, MG, 35501-296, Brazil.
  • Pimenta LPS; Department of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, 31270-90, Brazil.
  • Romão W; Petroleomic and Forensic Laboratory, Chemistry Department, Federal University of Espírito Santo, Vitória, ES, 29075-910, Brazil.
  • Santos HB; Federal Institute of Education, Science and Technology of Espírito Santo, Vila Velha, ES, 29106-010, Brazil.
  • Thomé RG; Tissue Processing Laboratory, Federal University of São João del Rei (UFSJ), 400, Sebastião Gonçalves Coelho, Chanadour, Divinópolis, MG, Brazil.
  • Reis RM; Tissue Processing Laboratory, Federal University of São João del Rei (UFSJ), 400, Sebastião Gonçalves Coelho, Chanadour, Divinópolis, MG, Brazil.
  • de Azambuja Ribeiro RIM; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, 14784-400, Brazil. ruireis.hcb@gmail.com.
Invest New Drugs ; 38(4): 1044-1055, 2020 08.
Article in En | MEDLINE | ID: mdl-31781904
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Full text: 1 Database: MEDLINE Main subject: Chromones / Glioblastoma / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Year: 2020 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Chromones / Glioblastoma / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Year: 2020 Type: Article