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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.
Khattar, Ekta; Maung, Kyaw Ze Ya; Chew, Chen Li; Ghosh, Arkasubhra; Mok, Michelle Meng Huang; Lee, Pei; Zhang, Jun; Chor, Wei Hong Jeff; Cildir, Gökhan; Wang, Chelsia Qiuxia; Mohd-Ismail, Nur Khairiah; Chin, Desmond Wai Loon; Lee, Soo Chin; Yang, Henry; Shin, Yong-Jae; Nam, Do-Hyun; Chen, Liming; Kumar, Alan Prem; Deng, Lih Wen; Ikawa, Masahito; Gunaratne, Jayantha; Osato, Motomi; Tergaonkar, Vinay.
Affiliation
  • Khattar E; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Maung KZY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Chew CL; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Ghosh A; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Mok MMH; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
  • Lee P; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Zhang J; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, 210023, Nanjing, P.R. China.
  • Chor WHJ; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Cildir G; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Wang CQ; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Mohd-Ismail NK; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Chin DWL; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
  • Lee SC; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
  • Yang H; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
  • Shin YJ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
  • Nam DH; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Republic of Korea.
  • Chen L; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Republic of Korea.
  • Kumar AP; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, 210023, Nanjing, P.R. China.
  • Deng LW; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
  • Ikawa M; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Gunaratne J; Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Osato M; Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.
  • Tergaonkar V; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A-STAR), Singapore, Singapore.
Nat Commun ; 10(1): 5349, 2019 12 13.
Article in En | MEDLINE | ID: mdl-31836706
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Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / Rap1 GTP-Binding Proteins / Telomere-Binding Proteins / Carcinogenesis / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Hematopoietic Stem Cells / Rap1 GTP-Binding Proteins / Telomere-Binding Proteins / Carcinogenesis / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2019 Type: Article