Dexmedetomidine Protects SK-N-SH Nerve Cells from Oxidative Injury by Maintaining Iron Homeostasis.

Qiu, Lingqin; Ge, Li; Hu, Qionghua

Qiu, Lingqin; Ge, Li; Hu, Qionghua.

Affiliation

Qiu L; Department of Anesthesiology Gansu People's Hospital.
Ge L; Department of Anesthesiology Gansu People's Hospital.
Hu Q; Department of Anesthesiology Gansu People's Hospital.

Biol Pharm Bull ; 43(3): 424-431, 2020 Mar 01.

Article in En | MEDLINE | ID: mdl-31839625

Subject(s)

Dexmedetomidine/pharmacology; Iron/metabolism; Neurons/drug effects; Oxidative Stress/drug effects; Cell Survival/drug effects; Humans; JNK Mitogen-Activated Protein Kinases/drug effects; Reactive Oxygen Species/metabolism; STAT4 Transcription Factor/metabolism; Sp1 Transcription Factor/metabolism; tert-Butylhydroperoxide/pharmacology; tert-Butylhydroperoxide/toxicity

Key words

Dexmedetomidine; SK-N-SH cell; ferroptosis; labile ferrous ion

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Full text: 1 Database: MEDLINE Main subject: Oxidative Stress / Dexmedetomidine / Iron / Neurons Limits: Humans Language: En Year: 2020 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Oxidative Stress / Dexmedetomidine / Iron / Neurons Limits: Humans Language: En Year: 2020 Type: Article